S5799
Sigma
Suberic acid bis(3-sulfo-N-hydroxysuccinimide ester) sodium salt
≥95% (H-NMR), powder
| Synonym: | Bis(sulfosuccinimidyl) suberate sodium salt, BS3 |
| CAS Number: | 82436-77-9 |
| Linear Formula: | C16H18N2Na2O14S2 |
| Molecular Weight: | 572.43 |
| MDL number: | MFCD00054982 |
Description
| Application | Water soluble, homobifunctional cross-linking reagent with amine reactivity. Typically coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Useful for preparation of protein-protein, receptor-ligand and hapten carrier molecule conjugates. Incorporates 8-atom linker. |
Properties
| assay | ≥95% (H-NMR) |
| form | powder |
| solubility | H2O: 10 mg/mL |
| DMF: soluble | |
| storage temp. | −20°C |
Safety
References
| reference | Staros, J.V., N-hydroxysulfosuccinimide active esters: bis(N-hydroxysulfosuccinimide) esters of two dicarboxylic acids are hydrophilic, membrane-impermeant, protein cross-linkers. Biochemistry 21, 3950, (1982) Abstract |
| Staros, J.V., N-hydroxysulfosuccinimide active esters: bis(N-hydroxysulfosuccinimide) esters of two dicarboxylic acids are hydrophilic, membrane-impermeant, protein cross-linkers. Biochemistry 21, 3950, (1982) Abstract |
